On May 19, 2022, the V Annual All-Russian Scientific and Practical Conference with international participation “Safety of Pharmacotherapy: Noli nocere!” was held at the RMANPE, which was held as part of the XIII All-Russian Meeting “Actual Issues of Clinical Pharmacology and Drug Supply”.

In the work of the conference "Safety of pharmacotherapy: Noli nocere!" more than 400 students from 112 cities of Russia took part, including doctors of various specialties, residents, graduate students, young scientists, teachers of Russian medical universities, employees of pharmacies, pharmaceutical enterprises and companies.

The main organizers of the event were the Russian Medical Academy of Continuing Professional Education, Kazan State Medical Academy - a branch of RMANPO, Interregional Public Organization "Association of Clinical Pharmacologists", and ANO "National Scientific Center for Pharmacovigilance".

Farida Yarkaeva, Doctor of Pharmacy, Deputy Minister of Health of the Republic of Tatarstan (Kazan), Dmitry Sychev, Doctor of Medical Sciences, Professor, Professor of the Russian Academy of Sciences, Corresponding Member of the Russian Academy of Sciences, Head of the Department clinical pharmacology and therapy namede after academician B.E. Votchala, Rector of FGBOU DPO RMANPE of the Ministry of Health of Russia (Moscow), Rustem Khasanov, Doctor of Medical Sciences, Professor, Corresponding Member of the Russian Academy of Sciences, Director of KSMA.

The purpose of the event was to increase the level of knowledge of specialists in matters of personalized medicine, clinical pharmacology, tolerability and adverse drug reactions, pharmacovigilance, drug interactions and the safety of pharmacotherapy for somatic diseases and comorbid conditions.

The conference program broadly covered the issues of pharmacology, pharmacotherapy, clinical pharmacology, pharmacovigilance, drug interactions, efficacy and safety of modern drugs, geriatrics, personalized medicine, drug interchangeability, drug research and others, and was focused not only on the medical community of listeners, but and health care organizers, pharmacists, pharmacists, as well as specialists in the field of drug registration, pharmacoeconomics and pharmacoepidemiology.

“This year the conference has significantly expanded its audience and the range of topics covered. Particular attention will be paid to the issues of interchangeability of medicines. In the conditions of the tasks set for the medical professional community by the country's leadership and consumers of medicines, the issues of the emergence and research of domestic medicines will be touched upon,” commented Maxim Maksimov, MD, Professor, Dean of the Faculty of Preventive Medicine and Health Organization of the RMANPO, Head of the Department of Clinical Pharmacology and Pharmacotherapy of KSMA, Chief Freelance Specialist Clinical Pharmacologist of the Ministry of Health of the Republic of Tatarstan (Moscow).

For the first time this year, within the framework of the conference, issues of monitoring the effectiveness and safety of medicines and medical devices were considered. Reports were presented by all participants in the organization of the pharmacovigilance system: regulatory authorities, medical and pharmaceutical organizations, holders of registration certificates. The principles of state regulation of pharmacovigilance issues were discussed in detail in the report of Kirill Gorelov, Deputy Head of the Department for the Organization of State Quality Control of Medical Products, Head of the Pharmacovigilance Organization Department of the Federal Service for Surveillance in Healthcare (Moscow).

Corresponding Member of the Russian Academy of Sciences, Professor Dmitry Sychev devoted his speech to the challenges and modern approaches to solving the problems of monitoring security in medical organizations. The report of the rector of RMANPO presented the main clinical and pharmacological approaches and modern tools for managing the safety of drug therapy in a hospital. The introduction of such clinical and pharmacological tools for managing drug safety in real practice can significantly reduce the risks of drug errors and the number of adverse drug reactions.

The head of the Department of Pharmacology, St. Petersburg State University (St. Petersburg), Alexei Kolbin, presented modern approaches to the analysis of safety data using real-clinical data (RWD) at the plenary session. Many speakers discussed the relationship between pharmacogenetics and pharmacovigilance.

“Unlike pharmacoeconomics, which is now discussed not only by clinical pharmacologists, but by almost all medical disciplines, the topic of pharmacovigilance is almost never heard. It is very important that clinical pharmacologists pay attention to this problem Ike special attention,” said Alexey Kolbin.

The report of Boris Romanov, Doctor of Medical Sciences, Associate Professor, Head of the Department of Pharmacology of the Pediatric Faculty of the Federal State Autonomous Educational Institution of Higher Education Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of Russia (Moscow), dedicated to monitoring the safety of vaccines for the prevention of COVID-19.

Safe pharmacotherapy in special groups (pregnant women, children, etc.) was the subject of reports by Ekaterina Eliseeva, Doctor of Medical Sciences, Professor, Head of the Department of General and Clinical Pharmacology, Pacific State Medical University of the Ministry of Health of Russia, Chief Freelance Clinical Specialist pharmacologist of the Far Eastern Federal District (Vladivostok), Olga Reshetko, Doctor of Medical Sciences, Professor, Chief Freelance Clinical Pharmacologist of the Ministry of Health of Russia for the Volga Federal District, Head of the Department of Pharmacology, Saratov State Medical Faculty named after Razumovsky (Saratov), ​​and Dmitry Ivashchenko, Doctor of Medical Sciences, Associate Professor of the Department of Child Psychiatry and Psychotherapy, RMANPO (Moscow).

According to Ekaterina Eliseeva: “Clinical pharmacology has made a significant contribution to the healthcare system, to improving the efficiency and safety of therapy, and to organizing clinical trials. As for doctors representing other specialties, clinical pharmacology has long gone beyond the scope of a scientific discipline or an educational subject - today, no medical intervention can be imagined without pharmacotherapy. Today we work in the context of the use of genetically engineered drugs for the treatment of severe life-threatening orphan diseases, in the use of modern drugs in oncology, oncohematology, endocrinology, which allows us to maintain long years of quality life for those patients whose condition was literally 10-20 years ago by experts regarded as hopeless. The improvement of genetic methods of research makes its contribution, which enable a doctor of any specialty to personalize the selection of effective safe therapy for each patient. Therefore, it is impossible to imagine today any area of ​​medical activity that would not require an in-depth study of clinical pharmacology, and this means that today's conference is an event in which every doctor should take part.

In separate sections - "Pharmacovigilance in a medical organization" (moderators: Alexander Matveev, Ph.D., Associate Professor of the Department of Clinical Pharmacology and Therapy named after Academician B.E. Votchal, Head of the Academic Educational Center for Fundamental and Translational Medicine of the RMANPO (Moscow ), and Vitaly Polivanov, Head of the Center for Pharmacovigilance of the Federal State Budgetary Institution "IMCEUAOSMP" of Roszdravnadzor (Moscow) and "The Pharmacovigilance System at the DRU" (moderators: Renad Alyautdin, Doctor of Medical Sciences, Professor, Head of the Department for Expertise on the Safety of Medicines of the Federal State Budgetary Institution "Scientific Center for Expertise of Medicinal Products" of the Ministry of Health of Russia (Moscow), and Anatoly Krasheninnikov, Doctor of Pharmacy, General Director of ANO "NSC PHARMAKONADZORA", Head of the Department of Pharmacy of Pirogov Russian National Research Medical University (Moscow) , - discussed particular issues of pharmacovigilance in medical organizations and holders of registration certificates. the results of research studies on the safety of NSAIDs, drugs used in the treatment of COVID-19, antibiotics, and others are presented.

The results of the work of the leading regional centers of the Republic of Tatarstan (Irina Burashnikova, PhD, Associate Professor of the Department of Clinical Pharmacology and Pharmacotherapy of the KSMA, clinical pharmacologist of the Kazan branch of the Federal State Budgetary Institution "IMTSEUAOSMP" of Roszdravnadzor, Kazan) and the Sverdlovsk Region (Aelita Neganova) were presented to the attention of the participants , Candidate of Medical Sciences, Associate Professor, Head of the Center of GAUZ SO "SOKB No. 1", Yekaterinburg).

Separate reports were devoted to the importance of collecting information from pharmaceutical workers (Igor Yakovlev, Doctor of Pharmacy, Associate Professor, Head of the Department of Pharmacy, Professor of the Mari State University, Yoshkar-Ola), the importance of interaction between pharmaceutical companies and doctors (Olga Yermishina, Head of the Pharmacosafety Group at Bayer JSC), conducting clinical trials (Alina Mustafina, Lecturer at the Department of Medical Equipment, RMANPE, Moscow).

Of particular interest to the audience was the work of the section "Efficacy and safety of pharmacotherapy in special groups of patients", moderated by Galina Batishcheva, Doctor of Medical Sciences, Professor, Head of the Department of Clinical Pharmacology, FSBEI HE VSMU named after V.I. N.N. Burdenko, member of the profile commission of the Ministry of Health of Russia on clinical pharmacology, chief freelance specialist in clinical pharmacology of the Department of Health of the Voronezh region, Honored Doctor of the Russian Federation (Voronezh), and Maxim Maximov.

As Galina Batishcheva said: “I would like to express my deep gratitude to the organizers of the conference, because we missed the period of post-COVID disunity - we need not just information, we need fresh, relevant, lively communication with colleagues. On the other hand, there is the exchange of experience, which was voiced in the reports of colleagues from different regions, different medical universities, because over the years new information has been received related to the treatment of COVID-19, and post-COVID disorders, and the problems faced by clinical pharmacologists - antibiotic resistance, side effects of drug therapy, orphan diseases, pharmacoeconomic analysis, new effective treatment regimens. Therefore, the conference is necessary for both university employees and practical health care doctors. The controversy persists almost continuously. The theme of the conference on clinical pharmacology includes both traditional sections, which are always needed and in demand, and new topics, for example, post-COVID disorders.”

The program of the event was accredited by the Commission for the Evaluation of Training Activities and Materials in accordance with the established requirements for CME.

Organizer:
Center for the Development of Academic Projects of RMANPO
conference@rmapo.ru